The incident took place on the N6 about 15 km south of Redersburg, on its way to Smithfield and about 60 kilometers south of Bloemfontein.
The city to the city bus transported 33 passengers and clashed with a heavy vehicle.
According to Free State Emergency Management Services (EMS), five fatalities were initially confirmed and another five more deaths were reported after extrication efforts because some passengers were trapped in the wreck.
Seven people suffered moderate injuries, while two others have serious injury and are treated in hospitals in Bloemfontein.
Motorists are advised to take alternative routes due to a complete road closure in the area.
“At this stage we cannot confirm the exact cause of the fatal accident; that’s why the law enforcement is on site. They will then determine that at a later stage,” said EMS Sipho Towa.
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